Current treatment
Current Cycle
Antagonist · start 150 IU · dose 225 from D5 · antagonist from D7
| Clinical item | Day 18 Sep | Day 310 Sep | Day 512 Sep | Day 714 Sep | Day 815 Sep |
|---|---|---|---|---|---|
| MedicationIU | 150Gonadotropin | 150Gonadotropin | 225Gonadotropin | 225Gonadotropin + antagonist | 225Gonadotropin + antagonist |
| Estradiol (E2)pg/mL | 48 | 112 | 285 | 620 | 980 |
| LHmIU/mL | — | — | 3.1 | 3.8 | 4.0 |
| Progesterone (P4)ng/mL | — | — | 0.5 | 0.6 | 0.7 |
| Right ovarylead follicle, mm | — | 83 follicles | 113 follicles | 144 follicles | 175 follicles |
| Left ovarylead follicle, mm | — | 72 follicles | 103 follicles | 133 follicles | 164 follicles |
| Endometriummm | — | — | 5.8 | 7.1 | 8.4 |
Monitoring
Investigation Trends
Estradiol (E2)
pg/mL
980
LH
mIU/mL
4.0
Progesterone (P4)
ng/mL
0.7
Endometrium
mm
8.4
Clinical background
Fertility Baseline
Sara M. Female
Infertility duration
4 years, primary
Previous pregnancies
None
Ovarian reserve
AMH 1.4 ng/mL, AFC 11
Diagnoses
Diminished ovarian reserveStage II endometriosis
Uterine and tubal
Both tubes patent on HSG. Normal uterine cavity.
Genetics
Karyotype normal. No carrier screening abnormality.
Ahmed M. Partner
Semen assessment
Concentration 14 million/mL, motility 38%, normal forms 3%
Diagnosis
Mild oligoasthenoteratozoospermia
Previous treatment
None
Genetics
Karyotype normal. Y-chromosome microdeletion not detected.
Longitudinal record
Patient Journey
15 SEP
Hormonal investigations received
E2 980, LH 4.0, P4 0.7
15 SEP
Monitoring ultrasound performed
Lead follicle 17mm right, endometrium 8.4mm
14 SEP
Antagonist commenced
Lead follicle reached 14mm
12 SEP
Medication dose adjusted
Gonadotropin 150 to 225 IU
12 SEP
Monitoring ultrasound performed
10 SEP
Monitoring ultrasound performed
8 SEP
Treatment cycle commenced
IVF cycle 2, antagonist protocol
3 SEP
Consultation — readiness confirmed
Plan agreed for second IVF cycle
27 AUG 2026
Pre-cycle investigations completed
AMH, AFC, repeat semen analysis
18 AUG 2026
Consultation following failed cycle
Review of cycle 1 outcome
9 FEB 2026
Cycle 1 outcome recorded
Not successful
26 JAN 2026
Embryo transfer
One blastocyst transferred, two vitrified
21 JAN 2026
Oocyte retrieval
9 oocytes retrieved
12 JAN 2026
Treatment cycle commenced
IVF cycle 1, antagonist protocol